The Foetus as a Patient, The Evolving Challenge

Major advances in ultrasound, prenatal diagnosis and therapy, and fetal assessment are furthering fetal medicine and clinical perinatology. These developments include : progress in 3-dimensional and color Doppler ultrasound for insights into early embryonic structure and function, counseling for pre-embryonic research, genetic counseling and prenatal informed consent, the use of cardiotocograms (CTGs), ultrasound imaging, Doppler ultrasound, analysis of nucleated red blood cells, and a broad range of clinical topics ranging from the Internet to neonatal intensive care. Under the editorship of Dr. Frank Chervenak and Professors Asim Kurjak and Zoltan Papp, authors and editors of many respected books in this field, this book provides detailed, authoritative coverage of the latest developments in fetal medicine and clinical perinatology. Following an introductory chapter on the moral foundations of leadership in fetal medicine, the book presents 38 chapters in four sections dealing with new developments in ultrasound, the state of the art of prenatal diagnosis and therapy, the challenge of fetal assessment and current perspectives on clinical perinatology. The volume is extensively illustrated throughout and includes bibliographic references and index.

IntroductionThe moral foundations of leadership in fetal medicine, F. Chervenak, L. McCullough, A. Kurjak, Z. Papp New developments in ultrasoundThe assessment of morphological and vascular development of the early embryo, A. Kurjak, T. Hafner, I. Bekavac Threatened abortion: new insights by color Doppler, three- and 4-dimensional ultrasound, S. Kupesic, A. Kurjak, A. Aksamija Venous return in monochorionic twin pregnancy in the late first trimester, A. Matias and N. Montenegro First-trimester diagnosis of fetal abnormalities by two and three-dimensional sonoembryology, H. Takeuchi Chiari II malformation in the fetus, V. D'Addario, V. Pinto, L. Di Cagno Transvaginal three-dimensional volume assessment of the fetal brain structure, R. Pooh, K. Pooh Human fetal pulmonary arterial blood flow, JJ.A.M. Laudy, J.W. Wladimiroff Sonographic examination of the uterine cervix, T. Chaiworapongsa, J. Espinoza, K. Kalache, M.-T. Gervasi, R. Romero The state of the art of prenatal diagnosis and therapyMedical and ethical aspects of pre-embryo research, J.G. Schenker The change in public demand for genetic counseling in the last 25 years, Z. Papp Prenatal informed consent for sonogram: the time for first-trimester nuchal translucency has come, S.T. Chasen, D.W. Skupski, L.B. McCullough, F.A. Chervenak Prenatal diagnosis of fetal cells in maternal blood by comparative genomic hybridization, Y.H. Yang, S.H. Kim, J.E. Jung Prenatal diagnosis of hemoglobinopathies, A.J. Antsaklis Prenatal diagnosis of b-thalassemia: Sardinian experience of 6000 cases, G. Monni, M.A. Zoppi, R.M. Ibba Amniocentesis, T. Stefos Selective reduction, M.I. Evans, R.J. Wapner The challenge of fetal assessmentEvaluation of intrapartum long-term cardiotocography with artificial neural network analysis, K. Maeda, M. Utsu, Y. Noguchi, F. Matsumoto Objective definition of intrauterine growth restriction and practical consequences, G. Mandruzzato, Y.J. Meir, G. Maso, L. Fischer Fetal risks of macrosomia, V. Váradi Normal and abnormal growth in multiple pregnancies, I. Blickstein Twin-twin transfusion syndrome, R.A. Quintero Non-immune fetal hydrops, H.N. Winn Advances in the diagnosis of intrapartum asphyxia, R. Luzietti, G. Clerici, K.G. Rosen, G.C. di Renzo The role of nucleated red blood cells in obstetrics, M.Y. Divon, A. Ferber Current perspectives on clinical perinatologyPerinatal medicine in the information age, I.E. Zador, S.C. Blackwell, R.J. Sokol, M.I. Evans Low-molecular-weight heparin in perinatal medicine, D. Blickstein, I. Bickstein Breast cancer and pregnancy, E. Mathieu, P. Merviel, E. Barranger, J.M. Antoine, S. Uzan Substance abuse during pregnancy, L.S. Voto, A.J. Siufi The dilemma of toxoplasmosis, M. Mahran Should we be using repeated doses of antenatal corticosteroids? J.P. Newnham, T.J.M. Moss, I. Nitsos, D. Sloboda, J. Challis Fetal macrosomia: prediction, timing, and mode of delivery, C. Yabes-Almirante Clinical dimensions of pre-eclampsia, E.V. Cosmi, F. Pierucci, G.M. Terracina, R. La Torre, L. Maranghi, E. Cosmi, M.M. Anceschi Pathophysiology of pre-eclampsia, P. Merviel, L. Carbillon, J.-C. Challier, M. Beaufils, S. Uzan New therapeutic developments in brain-orientated intensive care in the term and preterm newborn, L. Cornette, M. Levene Index