Hydrogels in Drug Delivery Advances in the Manufacture, Characterization, and Application of Hydrogels to Address Current Global Healthcare Challenges

Langue : Anglais

Coordonnateurs : Paredes Alejandro J., Larrañeta Eneko, Laverty Garry, Donnelly Ryan F.

Résumé
Sommaire
Biographie
Commentaire

Hydrogels in Drug Delivery: Advances in the Manufacture, Characterization, and Application of Hydrogels to Address Current Global Healthcare Challenges covers a number of topics ranging from the basic chemistry of hydrogels to specific application of existent and novel hydrogels in controlled drug delivery and biomedicine. Hydrogels have been increasingly used in the development of novel formulations with application in a wide variety of therapeutic and monitoring purposes. Multidisciplinary work carried out by researchers working in synthetic chemistry, drug delivery, biomedicine and other fields led to the development of novel polymers enabling the preparation of hydrogels with adjustable physicochemical properties. Accordingly, these materials offer multiple advantages over other drug delivery systems, including an increased patient compliance by reducing the required number of medication doses, reducing the healing time in injuries, or simplifying patient monitoring by reducing the invasiveness of currently available methods.

1. Synthesis and chemistry of hydrogels
2. Characterization techniques of hydrogels in healthcare
3. Hydrogels in controlled drug delivery, mechanisms involved in drug delivery from hydrophilic matrices
4. Molecularly imprinted hydrogels in drug delivery
5. Protein-like hydrogels, synthesis, and applications in biomedicine
6. Stimuli responsive hydrogels in drug delivery and biomedicine
7. Hydrogel-forming microneedles
8. Injectable depot-forming hydrogels for long-acting drug delivery
9. Hydrogels for vaginal drug delivery and other applications
10. In situ gel forming formulations for topical drug delivery
11. The use of hydrogels in oral drug delivery
12. 3D-printed devices based on hydrogels in healthcare
13. Hydrogels and their application in tissue regeneration
14. The role of hydrogels in wound healing

Dr Alejandro Paredes is a pharmacist by training, graduated from the National University of Córdoba, Argentina (2011), where he also obtained his PhD (2016) and taught pharmaceutical sciences for 7 years. As a postdoctoral researcher, he visited the University of the Basque Country (Spain), the University of Pavia (Italy), and worked at Queen's University Belfast (UK). Dr Paredes is currently a Lecturer in Pharmaceutical Sciences at Queen’s University, where he teaches pharmaceutical technology and leads a research group that focuses on the development of precisely engineered nanocrystals and microneedles for tissue targeting. Dr Paredes has authored 49 scientific publications, including 44 papers, 3 patents and 3 book chapters (h-index 18, 798 citations). Dr Paredes has presented his work in multiple international conferences and is a member of several scientific societies and the editorial board of two internationally recognised journals.
Dr Eneko Larrañeta is a Lecturer in Pharmaceutical Sciences at the School of Pharmacy Queen’s University Belfast. He worked in different multidisciplinary first-class laboratories developing drug delivery systems. His research area falls within the interface of pharmaceutics, chemistry, engineering and biomedical sciences. During his independent career, he developed research projects for industrial partners (L’Oreal) and research councils (Wellcome Trust, Royal Society, PATH among others). To date, he has published more than 40 peer-reviewed papers in leading international journals, as well as 4 book chapters, 1 invited presentation and 11 conference abstracts, describing a range of advanced drug delivery systems, including nanoparticles and microneedles.
Dr Garry Laverty is a Senior Lecturer at the School of Pharmacy Queen’s University Belfast. His Biofunctional Nanomaterials group develop self-assembling hydrogel platforms for biomedical applications based on the building blocks of life, namely peptide and their unnatura

Covers the fundamental mechanisms of drug delivery from a hydrophilic matrix
Provides interconnections between introductory and applied materials chapters
Includes experimental pictures and links to multimedia features including videos and slides