Sample size calculations in clinical research (Biostatistics series) (2nd Ed.)
Langue : Anglais
Auteurs : CHOW Shein-Chung, SHAO Jun, WANG Hansheng
One of the few books to systematically summarize clinical research procedures, Sample Size Calculations in Clinical Research, Second Edition discusses numerous statistical procedures for sample size calculation that are commonly employed at various phases of clinical development. Each chapter includes, whenever possible, real-world examples of clinical studies from therapeutic areas to demonstrate the clinical and statistical concepts, interpretations, and their relationships and interactions. This edition contains new chapters that focus on three major areas of clinical research. It also covers sample size calculation topics that are currently under discussion in the fields of pharmaceutical research and development.
Introduction. Consideration Prior to Sample Size Calculation. Comparing Means. Large Sample Tests for Proportions. Exact Tests for Proportions. Tests for Goodness-of-Fit and Contingency. Comparing Time-to-Event Data. Group Sequential Methods. Comparing Variabilities. Bioequivalence Testing. Dose Response Studies. Microarray Studies. Bayesian Sample Size Calculation. Nonparametrics. Sample Size Calculation in Other Areas.
Date de parution : 06-2007
Ouvrage de 472 p.
Thème de Sample size calculations in clinical research... :
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