Optical Methods and Instrumentation in Brain Imaging and Therapy, 2013 Bioanalysis Series, Vol. 3

This book provides a comprehensive up-to-date review of optical approaches used in brain imaging and therapy. It covers a variety of imaging approaches including diffuse optical imaging, laser speckle imaging, photoacoustic imaging and optical coherence tomography. A number of laser-based therapeutic techniques are reviewed, including photodynamic therapy, fluorescence guided resection and photothermal therapy. Fundamental principles and instrumentation are discussed for each imaging and therapeutic approach.

PREFACE.- CHAPTER 1: OPTICAL PROPERTIES OF BRAIN TISSUE.- CHAPTER 2: HISTORY OF DIFFUSE OPTICAL SPECTROSCOPY OF HUMAN TISSUE.- CHAPTER 3: DIFFUSE OPTICAL TOMOGRAPHY FOR BRAIN IMAGING: CONTINUOUS WAVE INSTRUMENTATION AND LINEAR ANALYSIS METHODS.- CHAPTER 4: DIFFUSE OPTICAL TOMOGRAPHY FOR BRAIN IMAGING: THEORY.- CHAPTER 5: LASER SPECKLE IMAGING OF CEREBRAL BLOOD FLOW.- CHAPTER 6: PHOTOACOUSTIC TOMOGRAPHY OF THE BRAIN.- CHAPTER 7: OPTICAL COHERENCE TOMOGRAPHY FOR BRAIN IMAGING.- CHAPTER 8: DELINEATING NORMAL FROM DISEASED BRAIN BY AMINOLEVULINIC ACID INDUCED FLUORESCENCE.- CHAPTER 9: INTRACRANIAL PHOTODYNAMIC THERAPY.- CHAPTER 10: NANOPARTICLE-MEDIATED PHOTOTHERMAL THERAPY OF BRAIN TUMORS.- CHAPTER 11: PHOTO-ACTIVATED CANCER THERAPY: POTENTIAL FOR TREATMENT OF BRAIN TUMORS.- INDEX.